Concomitant pemphigus herpetiformis and sarcoidosis
نویسندگان
چکیده
Dsg: desmoglein H&E: hematoxylin-eosin IL: interleukin PH: pemphigus herpetiformis INTRODUCTION Pemphigus herpetiformis (PH) is a rare variant of pemphigus and accounts for approximately 7% of cases. PH combines the clinical features of dermatitis herpetiformis with the histologic features of pemphigus. Clinically, the plaques are herpetiform or even annular. PH follows a more benign course with mild skin disease and no mucosal involvement. The histopathology findings can be subtle with minimal to absent acantholysis and a mixed infiltrate of eosinophils and neutrophils. Biopsies, direct immunofluorescence, indirect immunofluorescence, and serum autoantibodies are required to make the diagnosis. Autoantibodies to desmoglein (Dsg) 1 are common, although Dsg3 and desmocollin 1 have been reported. We present a rare case of the simultaneous onset of PH and sarcoidosis.
منابع مشابه
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